Kotobuki pharmaceutical Co., Ltd.
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1. When we established our company:Active substances were extracted from medical herbs produced in Nagano prefecture.

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Apricot kernel water (antitussive, expectorant) was produced from apricots.


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scopolia extract(stomachic)wasere extracted from Scopolia japonica.


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senega syrup(antitussive・expectorant drug) was produced from senega



2. Synthetic medicine

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By chemically modifying Azulene contained in chamomile, Marzulene S combination Granules and Marzulene combination Tablet ES (therapeutic agent for gastritis, gastric ulcer and duodenum)and Azuloxa Granules 2.5%, Azuloxa tablets 15mg(therapeutic agent for gastric ulcer)were successfully developed.


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L-glutamine (therapeutic agent for gastritis, gastric ulcer and duodenum) contained in cabbage also serves as an ingredient of Marzulene S combination Granules and Marzulene combination Tablet ES.


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Study of chemical synthesis focusing on “sugar” which plays a wide variety of roles within organisms is also ongoing.